The entire volume of air in every room, or space, needs to be filtered so that all the pollutants and virus particles can be removed.
This air change should happen several times every hour, depending on the use of the room, number of occupants and other factors.
Once you know the ACH you can help to protect the health and wellbeing of everyone using that space, by checking whether you already have the right air purification or ventilation in place and knowing which steps to take if not.
For example, the ACH requirements of a room can help you work out exactly which type of air purifiers, and how many, you need for that space.